![]() ![]() Nevus flammeus nuchae ('stork bite' in common parlance) occurs in about 5% of persons. Reports of MTN in multiple members of families were also noted. There was male-to-male transmission in 1 family. Pasyk (1992) described 2 families with the lateral type of telangiectatic nevi in various locations of the body. In LTN, loss of peripheral nervous elements in the perivascular region is associated with reduced vasoactive responses to both vasodilating and vasoconstricting stimuli. In the case of MTN, however, there appears to be a defect in maturation of cutaneous sympathetic innervation. ![]() Both types show mature, ectatic capillaries with flat endothelium in the dermis, primarily in the superficial plexus. Whereas MTN is a frequent finding in newborns, LTN is relatively rare and usually persists throughout life. ![]() Pasyk (1992) made a distinction between medial telangiectatic nevus (MTN), also known as salmon patch, angel's kiss, and stork bite, and lateral telangiectatic nevus (LTN), more popularly called port-wine stain or nevus flammeus. Merlob and Reisner (1985) described a family in which nevus flammeus of both the forehead and the nape of the neck occurred in a mother and 2 daughters, while her son and her mother showed only nevus flammeus of the forehead. However, Shafar and Doig (1955), like Zumkeller (1957) and others, insisted on a genetic basis. Sklarz (1955) questioned the significance of genetic factors. An extensive pedigree demonstrating dominant inheritance was published by Zumkeller (1957). Unlike the frequent 'port-wine stains' of the forehead ( 163000), this is a persistent type of hemangioma. Sometimes called port-wine stains, these consist of a faint, nonelevated, red area of variable size and irregular outline on the nape of the neck. ![]()
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